Baclofen is a muscle relaxant and antispastic. Its chemical name is 4- amino-3- (4-chlorophenyl)- butanoic acid. The structural formula is represented below:Baclofen is a white to off-white, odorless or practically odorless crystalline powder, with a molecular weight of 213.66. It is slightly soluble in water, very slightly soluble in methanol, and insoluble in chloroform.Baclofen tablets are available as 10-mg and 20-mg tablets for oral administration.
Kemstro’s (baclofen orally disintegrating tablets) inactive ingredients: KEMSTRO is available as 10 mg and 20 mg orally disintegrating tablets. Each orally disintegrating tablet also contains as inactive ingredients: aspartame, colloidal silicon dioxide, crospovidone, magnesium stearate, mannitol, microcrystalline cellulose, natural and artificial orange flavor and povidone.
Baclofen tablets: Cellulose compounds, magnesium stearate, povidone, and starch.
Baclofen injection: is a sterile, pyrogen-free, isotonic solution free of antioxidants, preservatives or other potentially neurotoxic additives indicated only for intrathecal administration. The drug is stable in solution at 37° C and compatible with CSF. Each milliliter of baclofen injection contains baclofen U.S.P. 500 mcg or 2000 mcg and sodium chloride 9 mg in Water for Injection; pH range is 5-7. Each ampule is intended for SINGLE USE ONLY. Discard any unused portion. DO NOT AUTOCLAVE.

Common uses
This medicine is a muscle relaxant used to treat muscle spasms associated with multiple sclerosis or spinal cord injuries. It may also be used to treat other conditions as determined by your doctor.
Before using
Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking. Do not start or stop any medicine without doctor or pharmacist approval. Inform your doctor of any other medical conditions including stroke, seizures, serious kidney problems, allergies, pregnancy, or breast-feeding.
Directions
Follow the directions for using this medicine provided by your doctor. Store this medicine at room temperature in a tightly-closed container, away from heat and light. If you miss a dose of this medicine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Cautions
Do not suddenly stop taking this medicine without checking with your doctor. Your doctor can tell you the best way to gradually reduce the dosage. This medicine may cause drowsiness or dizziness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to this medicine. This medicine will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.
For women: if you plan on becoming pregnant, discuss with your doctor the benefits and risks of using this medicine during pregnancy. This medicine is excreted in breast milk. If you are or will be breast-feeding while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby.
Possible side effects
Side effects, that may go away during treatment, include drowsiness or difficulty sleeping, dizziness, fatigue, nausea, constipation, or headache. If they continue or are bothersome, check with your doctor. Check with your doctor as soon as possible if you experience confusion, frequent urination, vomiting, increased weakness of arms or legs, blurred vision, or slurred speech.An allergic reaction to this medicine is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include rash, itching, swelling, dizziness, or trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.
If you take too much
If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include vomiting, muscle weakness, drowsiness, slow breathing, and seizures.
Additional information
Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. Keep this medicine out of the reach of children. If using this medicine for an extended period of time, obtain refills before your supply runs out.
Drug interactions
Drug interactions can result in unwanted side effects or prevent a medicine from doing its job. Some medicines or medical conditions may interact with this medicine. Inform your doctor or pharmacist of all prescription and over-the-counter medicine that you are taking.